Our team is dedicated to exploring the intricate interactions between proteins and various biomolecules, including ligands, sugars, peptides, and polymers. Understanding these interactions is crucial for deciphering the biochemical pathways that govern cellular functions and for developing new therapeutic strategies. To investigate these complex interactions, we employ a range of biophysical techniques that provide detailed insights at a molecular level. Our primary tool is nuclear magnetic resonance (NMR) spectroscopy, which allows us to capture dynamic information about protein conformation and binding mode. Protein currently studied: TSPO, Pin1, FABP, HDM2, lectins Key Collaborations and Applications Our work is strengthened by collaborations with leading research groups: • Claire Loison (ILM, Lyon): MD simulations • Luminita Duma (ICMR, Reims): Liquid and Solid States NMR, Protein expression • Jérôme Boisbouvier, Lionel Imbert (IBS, Grenoble): Cell Free protein expression • Catherine Duport Dit Rousseau (SQPOV, Avignon): microbiologie • Alberta Ferrarini (Chemistry Dpt, Univ. Padova): MD simulations • Daniel Da Silva (Univ. Palacky, Olomouc): Cellulose chemistry